Biological Response Modifier

The beginning of the study on BRM

During injection of anti-cancer drugs, destructions of healthy cells along with cancer cells occur resulting in problem of weakened white blood cell activation. And because of this problem, side effects and infectious disease occur when anti-cancer drug is injected.

To solve this problem, the development of BRM has started. Thanks to its development, white blood cell is activated even during anti-cancer drug injection enabling it to attack cancer cells, cause synergy effect of immune system and the anti-cancer drug, and eventually lead to reducing the anti-cancer drug dosage to suppress side effects to minimum.

 

 

BRM drugs

Lentinan, and Picibanil are used for cancer treatment. It is difficult to inject proper dosage by IV, has side effects.  However, despite of the negative factors, BRM drugs are very valuable because cancer is a very serious disease.

 

 

Discovery of safe & easy to take BRM

Among the foods that we eat, there are many that help to regulate immunity and they are less effective compared to synthetic drug. Immunogenic probiotics which is the natural food that has the same level of efficacy as BRM in pharmaceuticals has been found through recent years of study. 

 

It is worth noting that the immunobiotics has no reports of any side effects.

 

The immunobiotics, which does not stress the body while having an effect comparable to pharmaceuticals is suitable for BRM material. In addition, the fact that it is ‘effective after the intake’ and that ‘it is safe’ is different from the existing BRM.

 

The high concentratedslain (Dead) bacteria of CUOME is a primium 100% pure strain without filtering concentration procedure that causes a negative effect on immune activation and also without additives such as kito acid etc. to increase the gathering ratio after cultivation of microbes.    

The Heat-killed bacteria of CUOME is also a immune speciallized primium strain with very low gathering rate and  the world's highest concentrated probiotics, which contains more than 8 trillion coccus bacteria per gram (5 trillion coccus bacteria per gram).

 

And in each lot, the dead bacteria material of CUOME, immunobiotics, goes through strict QC(Quality Control) by immune activation comparing test at the pharmaceutical level.

 

 

 

 

Effects of CUOME's Heat-killed lac tic acid bacteria as Immunobiotics

 

1. Promotes TNF production

2. Increase the macrophage to activate

3. Increase neutrophil to activate

4. Activate T cells

5. Activate NK cells

6. Improvement of bone marrow (lymphocyte factory) function