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Let's know the species of lactic acid bacteria and eat! 

Probiotics ingested enters through microfold cells (M-cells) of Peyer's patch, an immune organ in the small intestine and stimulates macrophages or dendritic cells to induce secretion of cytokines such as IL-12 and differentiation of T cells to activate an immune system.

The activated immune system responds to infection, removes cancer cells, and modulate immune system suppressing an atopy and autoimmune diseases, maintaining our body in a healthy state. (Keep homeostasis)

Most consumers of these probiotics products might think that they are all the same or similar when they are called just “lactic acid bacteria or probiotics” but there are many different types of probiotics.

Bacteria differs in shape and well-proliferating food group depending on the species, and the composition and content of the cells are also all different.

Therefore, the degree of immune activity occurring in our body might vary depending on the type of bacteria ingested.

As shown in the table above, when measuring the immune activity of mice fed with heat-killed probiotics, it can be seen that the expression level of IL-12 varies depending on the species.

IL-12 activates the immunity as an immune mediator produced by dendritic cells, macrophages, and neutrophils in response to antigenic stimulation.

The expression level of IL-12 was found to be the highest in Lactobacillus plantarum species.

The exact mechanism on difference of immune activity according to bacterial species needs to be studied more.

But It is certain that L. plantarum is a strain with high immune activity, and it is effective to obtain efficacy for immunity by ingesting it at a high concentration.

CUOME's LPQ1 is a product obtained by heat-treating L. plantarum Q1 safely, a strain with high immune activity at a high concentration.

This product could be ingested safely with high efficacy on immune activity.